Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study.
The mechanisms that underlie the development and maintenance of autoimmunity in myasthenia gravis are poorly understood.In this investigation, we evaluate the role of survivin, a member of the inhibitor whirlwind direct2 of apoptosis protein family, in humans and in two animal models.We identified survivin expression in cells with B lymphocyte and